Cargando…
Proposal for Alzheimer’s diagnosis using molecular buffer and bus network
A novel design of an optical trapping tool for tangle protein (tau tangles, β-amyloid plaques) and molecular motor storage and delivery using a PANDA ring resonator is proposed. The optical vortices can be generated and controlled to form the trapping tools in the same way as the optical tweezers. I...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3148847/ https://www.ncbi.nlm.nih.gov/pubmed/21822383 http://dx.doi.org/10.2147/IJN.S22165 |
_version_ | 1782209380707467264 |
---|---|
author | Mitatha, S Moongfangklang, N Jalil, MA Suwanpayak, N Saktioto, T Ali, J Yupapin, PP |
author_facet | Mitatha, S Moongfangklang, N Jalil, MA Suwanpayak, N Saktioto, T Ali, J Yupapin, PP |
author_sort | Mitatha, S |
collection | PubMed |
description | A novel design of an optical trapping tool for tangle protein (tau tangles, β-amyloid plaques) and molecular motor storage and delivery using a PANDA ring resonator is proposed. The optical vortices can be generated and controlled to form the trapping tools in the same way as the optical tweezers. In theory, the trapping force is formed by the combination between the gradient field and scattering photons, and is reviewed. By using the intense optical vortices generated within the PANDA ring resonator, the required molecular volumes can be trapped and moved dynamically within the molecular buffer and bus network. The tangle protein and molecular motor can transport and connect to the required destinations, enabling availability for Alzheimer’s diagnosis. |
format | Online Article Text |
id | pubmed-3148847 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Dove Medical Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-31488472011-08-05 Proposal for Alzheimer’s diagnosis using molecular buffer and bus network Mitatha, S Moongfangklang, N Jalil, MA Suwanpayak, N Saktioto, T Ali, J Yupapin, PP Int J Nanomedicine Original Research A novel design of an optical trapping tool for tangle protein (tau tangles, β-amyloid plaques) and molecular motor storage and delivery using a PANDA ring resonator is proposed. The optical vortices can be generated and controlled to form the trapping tools in the same way as the optical tweezers. In theory, the trapping force is formed by the combination between the gradient field and scattering photons, and is reviewed. By using the intense optical vortices generated within the PANDA ring resonator, the required molecular volumes can be trapped and moved dynamically within the molecular buffer and bus network. The tangle protein and molecular motor can transport and connect to the required destinations, enabling availability for Alzheimer’s diagnosis. Dove Medical Press 2011 2011-06-14 /pmc/articles/PMC3148847/ /pubmed/21822383 http://dx.doi.org/10.2147/IJN.S22165 Text en © 2011 Mitatha et al, publisher and licensee Dove Medical Press Ltd. This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited. |
spellingShingle | Original Research Mitatha, S Moongfangklang, N Jalil, MA Suwanpayak, N Saktioto, T Ali, J Yupapin, PP Proposal for Alzheimer’s diagnosis using molecular buffer and bus network |
title | Proposal for Alzheimer’s diagnosis using molecular buffer and bus network |
title_full | Proposal for Alzheimer’s diagnosis using molecular buffer and bus network |
title_fullStr | Proposal for Alzheimer’s diagnosis using molecular buffer and bus network |
title_full_unstemmed | Proposal for Alzheimer’s diagnosis using molecular buffer and bus network |
title_short | Proposal for Alzheimer’s diagnosis using molecular buffer and bus network |
title_sort | proposal for alzheimer’s diagnosis using molecular buffer and bus network |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3148847/ https://www.ncbi.nlm.nih.gov/pubmed/21822383 http://dx.doi.org/10.2147/IJN.S22165 |
work_keys_str_mv | AT mitathas proposalforalzheimersdiagnosisusingmolecularbufferandbusnetwork AT moongfangklangn proposalforalzheimersdiagnosisusingmolecularbufferandbusnetwork AT jalilma proposalforalzheimersdiagnosisusingmolecularbufferandbusnetwork AT suwanpayakn proposalforalzheimersdiagnosisusingmolecularbufferandbusnetwork AT saktiotot proposalforalzheimersdiagnosisusingmolecularbufferandbusnetwork AT alij proposalforalzheimersdiagnosisusingmolecularbufferandbusnetwork AT yupapinpp proposalforalzheimersdiagnosisusingmolecularbufferandbusnetwork |