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Daily Sampling of an HIV-1 Patient with Slowly Progressing Disease Displays Persistence of Multiple env Subpopulations Consistent with Neutrality
The molecular evolution of HIV-1 is characterized by frequent substitutions, indels and recombination events. In addition, a HIV-1 population may adapt through frequency changes of its variants. To reveal such population dynamics we analyzed HIV-1 subpopulation frequencies in an untreated patient wi...
Autores principales: | Skar, Helena, Gutenkunst, Ryan N., Wilbe Ramsay, Karin, Alaeus, Annette, Albert, Jan, Leitner, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149046/ https://www.ncbi.nlm.nih.gov/pubmed/21829600 http://dx.doi.org/10.1371/journal.pone.0021747 |
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