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Daily Sampling of an HIV-1 Patient with Slowly Progressing Disease Displays Persistence of Multiple env Subpopulations Consistent with Neutrality

The molecular evolution of HIV-1 is characterized by frequent substitutions, indels and recombination events. In addition, a HIV-1 population may adapt through frequency changes of its variants. To reveal such population dynamics we analyzed HIV-1 subpopulation frequencies in an untreated patient wi...

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Detalles Bibliográficos
Autores principales: Skar, Helena, Gutenkunst, Ryan N., Wilbe Ramsay, Karin, Alaeus, Annette, Albert, Jan, Leitner, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149046/
https://www.ncbi.nlm.nih.gov/pubmed/21829600
http://dx.doi.org/10.1371/journal.pone.0021747

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