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Culture of Mouse Embryonic Stem Cells with Serum but without Exogenous Growth Factors Is Sufficient to Generate Functional Hepatocyte-Like Cells
Mouse embryonic stem cells (mESC) have been used to study lineage specification in vitro, including towards a hepatocyte-like fate, and such investigations guided lineage differentiation protocols for human (h)ESC. We recently described a four-step protocol to induce hepatocyte-like cells from hESC...
Autores principales: | Pauwelyn, Karen, Roelandt, Philip, Notelaers, Tineke, Sancho-Bru, Pau, Fevery, Johan, Verfaillie, Catherine M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149071/ https://www.ncbi.nlm.nih.gov/pubmed/21829697 http://dx.doi.org/10.1371/journal.pone.0023096 |
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