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Deep and Highly Sensitive Proteome Coverage by LC-MS/MS Without Prefractionation

In-depth MS-based proteomics has necessitated fractionation of either proteins or peptides or both, often requiring considerable analysis time. Here we employ long liquid chromatography runs with high resolution coupled to an instrument with fast sequencing speed to investigate how much of the prote...

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Detalles Bibliográficos
Autores principales:	Thakur, Suman S., Geiger, Tamar, Chatterjee, Bhaswati, Bandilla, Peter, Fröhlich, Florian, Cox, Juergen, Mann, Matthias
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Biochemistry and Molecular Biology 2011
Materias:	Technological Innovation and Resources
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149084/ https://www.ncbi.nlm.nih.gov/pubmed/21586754 http://dx.doi.org/10.1074/mcp.M110.003699

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