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Tissue-specific expression of B7x protects from CD4 T cell–mediated autoimmunity

B7x, an inhibitory member of the B7/CD28 superfamily, is highly expressed in a broad range of nonhematopoietic organs, suggesting a role in maintaining peripheral tolerance. As endogenous B7x protein is expressed in pancreatic islets, we investigated whether the molecule inhibits diabetogenic respon...

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Detalles Bibliográficos
Autores principales:	Wei, Joyce, Loke, P’ng, Zang, Xingxing, Allison, James P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149222/ https://www.ncbi.nlm.nih.gov/pubmed/21727190 http://dx.doi.org/10.1084/jem.20100639

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