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The Rate of Interleukin-1β Secretion in Different Myeloid Cells Varies with the Extent of Redox Response to Toll-like Receptor Triggering

Human myeloid cells activate the NLRP3 inflammasome and secrete interleukin (IL)-1β in response to various Toll-like receptor (TLR) ligands, but the rate of secretion is much higher in primary human monocytes than in cultured macrophages or THP-1 cells. The different myeloid cells also display diffe...

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Detalles Bibliográficos
Autores principales:	Carta, Sonia, Tassi, Sara, Pettinati, Ilaria, Delfino, Laura, Dinarello, Charles A., Rubartelli, Anna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2011
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149300/ https://www.ncbi.nlm.nih.gov/pubmed/21628463 http://dx.doi.org/10.1074/jbc.M110.203398

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