Observation of cone and rod photoreceptors in normal subjects and patients using a new generation adaptive optics scanning laser ophthalmoscope

We demonstrate the capability of a new generation adaptive optics scanning laser ophthalmoscope (AOSLO) to resolve cones and rods in normal subjects, and confirm our findings by comparing cone and rod spacing with published histology measurements. Cone and rod spacing measurements are also performed...

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Autores principales: Merino, David, Duncan, Jacque L., Tiruveedhula, Pavan, Roorda, Austin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Optical Society of America 2011
Materias:
Ophthalmology Applications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149518/
https://www.ncbi.nlm.nih.gov/pubmed/21833357
http://dx.doi.org/10.1364/BOE.2.002189
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author Merino, David
Duncan, Jacque L.
Tiruveedhula, Pavan
Roorda, Austin
author_facet Merino, David
Duncan, Jacque L.
Tiruveedhula, Pavan
Roorda, Austin
author_sort Merino, David
collection PubMed
description We demonstrate the capability of a new generation adaptive optics scanning laser ophthalmoscope (AOSLO) to resolve cones and rods in normal subjects, and confirm our findings by comparing cone and rod spacing with published histology measurements. Cone and rod spacing measurements are also performed on AOSLO images from two different diseased eyes, one affected by achromatopsia and the other by acute zonal occult outer retinopathy (AZOOR). The potential of AOSLO technology in the study of these and other retinal diseases is illustrated.
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spelling pubmed-31495182011-08-10 Observation of cone and rod photoreceptors in normal subjects and patients using a new generation adaptive optics scanning laser ophthalmoscope Merino, David Duncan, Jacque L. Tiruveedhula, Pavan Roorda, Austin Biomed Opt Express Ophthalmology Applications We demonstrate the capability of a new generation adaptive optics scanning laser ophthalmoscope (AOSLO) to resolve cones and rods in normal subjects, and confirm our findings by comparing cone and rod spacing with published histology measurements. Cone and rod spacing measurements are also performed on AOSLO images from two different diseased eyes, one affected by achromatopsia and the other by acute zonal occult outer retinopathy (AZOOR). The potential of AOSLO technology in the study of these and other retinal diseases is illustrated. Optical Society of America 2011-07-08 /pmc/articles/PMC3149518/ /pubmed/21833357 http://dx.doi.org/10.1364/BOE.2.002189 Text en ©2011 Optical Society of America http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 Unported License, which permits download and redistribution, provided that the original work is properly cited. This license restricts the article from being modified or used commercially.
spellingShingle Ophthalmology Applications
Merino, David
Duncan, Jacque L.
Tiruveedhula, Pavan
Roorda, Austin
Observation of cone and rod photoreceptors in normal subjects and patients using a new generation adaptive optics scanning laser ophthalmoscope
title Observation of cone and rod photoreceptors in normal subjects and patients using a new generation adaptive optics scanning laser ophthalmoscope
title_full Observation of cone and rod photoreceptors in normal subjects and patients using a new generation adaptive optics scanning laser ophthalmoscope
title_fullStr Observation of cone and rod photoreceptors in normal subjects and patients using a new generation adaptive optics scanning laser ophthalmoscope
title_full_unstemmed Observation of cone and rod photoreceptors in normal subjects and patients using a new generation adaptive optics scanning laser ophthalmoscope
title_short Observation of cone and rod photoreceptors in normal subjects and patients using a new generation adaptive optics scanning laser ophthalmoscope
title_sort observation of cone and rod photoreceptors in normal subjects and patients using a new generation adaptive optics scanning laser ophthalmoscope
topic Ophthalmology Applications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149518/
https://www.ncbi.nlm.nih.gov/pubmed/21833357
http://dx.doi.org/10.1364/BOE.2.002189
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