Cargando…

Unique CRF01_AE Gag CTL Epitopes Associated with Lower HIV-Viral Load and Delayed Disease Progression in a Cohort of HIV-Infected Thais

Cytotoxic T Lymphocytes (CTLs) play a central role in controlling HIV-replication. Although numerous CTL epitopes have been described, most are in subtype B or C infection. Little is known about CTL responses in CRF01_AE infection. Gag CTL responses were investigated in a cohort of 137 treatment-naï...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mori, Masahiko, Sriwanthana, Busarawan, Wichukchinda, Nuanjun, Boonthimat, Chetsada, Tsuchiya, Naho, Miura, Toshiyuki, Pathipvanich, Panita, Ariyoshi, Koya, Sawanpanyalert, Pathom
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149616/ https://www.ncbi.nlm.nih.gov/pubmed/21826201 http://dx.doi.org/10.1371/journal.pone.0022680

Ejemplares similares

The Effect of HLA Polymorphisms on the Recognition of Gag Epitopes in HIV-1 CRF01_AE Infection
por: Sriwanthana, Busarawan, et al.
Publicado: (2012)

HLA-Associated Immune Pressure on Gag Protein in CRF01_AE-Infected Individuals and Its Association with Plasma Viral Load
por: Gesprasert, Goragoch, et al.
Publicado: (2010)

Incidence and predictors of regimen-modification from first-line antiretroviral therapy in Thailand: a cohort study
por: Tsuchiya, Naho, et al.
Publicado: (2014)

Deficiency of mannose-binding lectin is a risk of Pneumocystis jirovecii pneumonia in a natural history cohort of people living with HIV/AIDS in Northern Thailand
por: Yanagisawa, Kunio, et al.
Publicado: (2020)

CRF01_AE-Specific Neutralizing Activity Observed in Plasma Derived from HIV-1-Infected Thai Patients Residing in Northern Thailand: Comparison of Neutralizing Breadth and Potency between Plasma Derived from Rapid and Slow Progressors
por: Sapsutthipas, Sompong, et al.
Publicado: (2013)

Molecular Evolution of HIV-1 CRF01_AE Env in Thai Patients
por: Boonchawalit, Samatchaya, et al.
Publicado: (2011)

Lymphoproliferative responses to HIV-1 Gag p24 antigen and mitogens in HIV-1 subtype CRF01_AE infected Thai patients and HIV-1 seronegative donors
por: Chuenchitra, Thippawan, et al.
Publicado: (2006)

Development of a Novel In Silico Docking Simulation Model for the Fine HIV-1 Cytotoxic T Lymphocyte Epitope Mapping
por: Mori, Masahiko, et al.
Publicado: (2012)

Correction: The Effect of HLA Polymorphisms on the Recognition of Gag Epitopes in HIV-1 CRF01_AE Infection
Publicado: (2014)

A replication study confirms the association of GWAS-identified SNPs at MICB and PLCE1 in Thai patients with dengue shock syndrome
por: Dang, Tran Ngoc, et al.
Publicado: (2014)

Chronic hepatitis B and C co-infection increased all-cause mortality in HAART-naive HIV patients in northern Thailand
por: TSUCHIYA, N., et al.
Publicado: (2013)

Analysis of temporal changes in HIV-1 CRF01_AE gag genetic variability and CD8 T-cell epitope evolution
por: Rafaqat, Wardah, et al.
Publicado: (2022)

A Novel Immunodominant CD8+ T Cell Response Restricted by a Common HLA-C Allele Targets a Conserved Region of Gag HIV-1 Clade CRF01_AE Infected Thais
por: Buranapraditkun, Supranee, et al.
Publicado: (2011)

Multi-layered Gag-specific immunodominant responses contribute to improved viral control in the CRF01_AE subtype of HIV-1-infected MSM subjects
por: Jiang, Fanming, et al.
Publicado: (2016)

Increased predominance of HIV-1 CRF01_AE and its recombinants in the Philippines
por: Chen, Yue, et al.
Publicado: (2019)

Susceptibility of HIV-1 Subtypes B′, CRF07_BC and CRF01_AE that Are Predominantly Circulating in China to HIV-1 Entry Inhibitors
por: Yu, Xiaoling, et al.
Publicado: (2011)

Association of BAK1 single nucleotide polymorphism with a risk for dengue hemorrhagic fever
por: Dang, Tran Ngoc, et al.
Publicado: (2016)

Cross-Continental Dispersal of Major HIV-1 CRF01_AE Clusters in China
por: An, Minghui, et al.
Publicado: (2020)

HIV-1 CRF01_AE strain is associated with faster HIV/AIDS progression in Jiangsu Province, China
por: Chu, Minjie, et al.
Publicado: (2017)

Phylogenetic Dependency Networks: Inferring Patterns of CTL Escape and Codon Covariation in HIV-1 Gag
por: Carlson, Jonathan M., et al.
Publicado: (2008)

Role of Transmitted Gag CTL Polymorphisms in Defining Replicative Capacity and Early HIV-1 Pathogenesis
por: Prince, Jessica L., et al.
Publicado: (2012)

Molecular Detection of HIV-1 Subtype B, CRF01_AE, CRF33_01B, and Newly Emerging Recombinant Lineages in Malaysia
por: Chook, Jack Bee, et al.
Publicado: (2015)

Characterization of two novel HIV-1 second-generation recombinants (CRF01_AE/CRF07_BC) identified in Hebei Province, China
por: Yang, Xuegang, et al.
Publicado: (2023)

Effects of CYP2B6 G516T polymorphisms on plasma efavirenz and nevirapine levels when co-administered with rifampicin in HIV/TB co-infected Thai adults
por: Uttayamakul, Sumonmal, et al.
Publicado: (2010)

Multiple Independent Introductions of HIV-1 CRF01_AE Identified in China: What Are the Implications for Prevention?
por: Abubakar, Yassir F., et al.
Publicado: (2013)

Limited Sustained Local Transmission of HIV-1 CRF01_AE in New South Wales, Australia
por: Di Giallonardo, Francesca, et al.
Publicado: (2019)

Intrapatient Development of Multi-Class Drug Resistance in an Individual Infected with HIV-1 CRF01_AE
por: Peng, Xiaorong, et al.
Publicado: (2021)

The Molecular Epidemiological and Immunological Characteristics of HIV-1 CRF01_AE/B Recombinants in Nanjing, China
por: Ge, You, et al.
Publicado: (2022)

Mutations in the V1 domain of Thai CRF01-AE viruses that confer sensitivity/resistance to broadly neutralizing antibodies
por: O'Rourke, S, et al.
Publicado: (2012)

Multiple CRF01_AE/CRF07_BC Recombinants Enhanced the HIV-1 Epidemic Complexity Among MSM in Shenyang City, Northeast China
por: He, Shan, et al.
Publicado: (2022)

Identification and genomic characterization of a novel HIV-1 unique recombinant form (CRF01_AE/CRF07_BC) in Zhejiang Province, China
por: Fan, Qin, et al.
Publicado: (2022)

HIV-1 CRF01_AE subtype and HIV-1 DNA level among patients with chronic HIV-1 infection: a correlation study
por: Lyu, Tingxia, et al.
Publicado: (2020)

Naturally Occurring Mutations in HIV-1 CRF01_AE Capsid Affect Viral Sensitivity to Restriction Factors
por: Nakayama, Emi E., et al.
Publicado: (2018)

1541 The Changing Molecular Epidemiology of HIV in the Philippines: Major Shift from Subtype B to CRF01_AE
por: Schwem, Brian, et al.
Publicado: (2014)

Tracing the epidemic history of HIV-1 CRF01_AE clusters using near-complete genome sequences
por: Li, Xingguang, et al.
Publicado: (2017)

Molecular Epidemiological Analysis of the Origin and Transmission Dynamics of the HIV-1 CRF01_AE Sub-Epidemic in Bulgaria
por: Alexiev, Ivailo, et al.
Publicado: (2021)

High prevalence of CXCR4 usage among treatment-naive CRF01_AE and CRF51_01B-infected HIV-1 subjects in Singapore
por: Ng, Kah Ying, et al.
Publicado: (2013)

Recombinant characteristics of three novel HIV-1 second-generation recombinant forms composed of CRF01_AE and CRF07_BC isolated in Hebei province, China
por: Lu, Xinli, et al.
Publicado: (2023)

The rapidly expanding CRF01_AE epidemic in China is driven by multiple lineages of HIV-1 viruses introduced in the 1990s
por: Feng, Yi, et al.
Publicado: (2013)

Characterization of Novel HIV-1 Intersubtype CRF01_AE/C and A1/C Recombinants from India
por: Pandey, Sudhanshu Shekhar, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_l6cf7ji8b8lie8ipocl320agql