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TRAPPC4-ERK2 Interaction Activates ERK1/2, Modulates Its Nuclear Localization and Regulates Proliferation and Apoptosis of Colorectal Cancer Cells

The trafficking protein particle complex 4 (TRAPPC4) is implicated in vesicle-mediated transport, but its association with disease has rarely been reported. We explored its potential interaction with ERK2, part of the ERK1/2 complex in the Extracellular Signal-regulated Kinase/ Mitogen-activated Pro...

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Detalles Bibliográficos
Autores principales: Zhao, Shu-Liang, Hong, Jie, Xie, Zuo-Quan, Tang, Jie-Ting, Su, Wen-Yu, Du, Wan, Chen, Ying-Xuan, Lu, Rong, Sun, Dan-Feng, Fang, Jing-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149646/
https://www.ncbi.nlm.nih.gov/pubmed/21826244
http://dx.doi.org/10.1371/journal.pone.0023262