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Alignment of transmembrane regions in the cystic fibrosis transmembrane conductance regulator chloride channel pore
Different transmembrane (TM) α helices are known to line the pore of the cystic fibrosis TM conductance regulator (CFTR) Cl(−) channel. However, the relative alignment of these TMs in the three-dimensional structure of the pore is not known. We have used patch-clamp recording to investigate the acce...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149817/ https://www.ncbi.nlm.nih.gov/pubmed/21746847 http://dx.doi.org/10.1085/jgp.201110605 |