B-Cell Depletion Therapy in Systemic Sclerosis: Experimental Rationale and Update on Clinical Evidence

Systemic sclerosis (SSc) is a systemic rheumatic disease with poor prognosis since therapeutic options are limited. Recent evidence from animal models suggests that B-cells may be actively involved in the fibrotic process. B-cells from tight skin mice, an animal model of scleroderma, display a “hype...

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Detalles Bibliográficos
Autores principales: Daoussis, Dimitrios, Liossis, Stamatis-Nick C., Yiannopoulos, Georgios, Andonopoulos, Andrew P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3150146/
https://www.ncbi.nlm.nih.gov/pubmed/21826145
http://dx.doi.org/10.1155/2011/214013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3150146/
https://www.ncbi.nlm.nih.gov/pubmed/21826145
http://dx.doi.org/10.1155/2011/214013

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