Boltzmann Energy-based Image Analysis Demonstrates that Extracellular Domain Size Differences Explain Protein Segregation at Immune Synapses

Immune synapses formed by T and NK cells both show segregation of the integrin ICAM1 from other proteins such as CD2 (T cell) or KIR (NK cell). However, the mechanism by which these proteins segregate remains unclear; one key hypothesis is a redistribution based on protein size. Simulations of this...

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Detalles Bibliográficos
Autores principales: Burroughs, Nigel J., Köhler, Karsten, Miloserdov, Vladimir, Dustin, Michael L., van der Merwe, P. Anton, Davis, Daniel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3150282/
https://www.ncbi.nlm.nih.gov/pubmed/21829338
http://dx.doi.org/10.1371/journal.pcbi.1002076

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3150282/
https://www.ncbi.nlm.nih.gov/pubmed/21829338
http://dx.doi.org/10.1371/journal.pcbi.1002076

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