High-Resolution Description of Antibody Heavy-Chain Repertoires in Humans

Antibodies' protective, pathological, and therapeutic properties result from their considerable diversity. This diversity is almost limitless in potential, but actual diversity is still poorly understood. Here we use deep sequencing to characterize the diversity of the heavy-chain CDR3 region,...

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Detalles Bibliográficos
Autores principales: Arnaout, Ramy, Lee, William, Cahill, Patrick, Honan, Tracey, Sparrow, Todd, Weiand, Michael, Nusbaum, Chad, Rajewsky, Klaus, Koralov, Sergei B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3150326/
https://www.ncbi.nlm.nih.gov/pubmed/21829618
http://dx.doi.org/10.1371/journal.pone.0022365

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3150326/
https://www.ncbi.nlm.nih.gov/pubmed/21829618
http://dx.doi.org/10.1371/journal.pone.0022365

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