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p53 Interacts with RNA Polymerase II through Its Core Domain and Impairs Pol II Processivity In Vivo
The tumor suppressor p53 principally functions as a gene-specific transcription factor. p53 triggers a variety of anti-proliferative programs by activating or repressing the transcription of effector genes in response to genotoxic stress. To date, much effort has been placed on understanding p53...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3150338/ https://www.ncbi.nlm.nih.gov/pubmed/21829606 http://dx.doi.org/10.1371/journal.pone.0022183 |