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Generation of a Cell Culture-Adapted Hepatitis C Virus with Longer Half Life at Physiological Temperature
BACKGROUND: We previously reported infectious HCV clones that contain the convenient reporters, green fluorescent protein (GFP) and Renilla luciferase (Rluc), in the NS5a-coding sequence. Although these viruses were useful in monitoring viral proliferation and screening of anti-HCV drugs, the infect...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3150383/ https://www.ncbi.nlm.nih.gov/pubmed/21829654 http://dx.doi.org/10.1371/journal.pone.0022808 |