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Broad Antibody Mediated Cross-Neutralization and Preclinical Immunogenicity of New Codon-Optimized HIV-1 Clade CRF02_AG and G Primary Isolates

Creation of an effective vaccine for HIV has been an elusive goal of the scientific community for almost 30 years. Neutralizing antibodies are assumed to be pivotal to the success of a prophylactic vaccine but previous attempts to make an immunogen capable of generating neutralizing antibodies to pr...

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Detalles Bibliográficos
Autores principales:	Agwale, Simon M., Forbi, Joseph C., Notka, Frank, Wrin, Terri, Wild, Jens, Wagner, Ralf, Wolf, Hans
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3150420/ https://www.ncbi.nlm.nih.gov/pubmed/21829720 http://dx.doi.org/10.1371/journal.pone.0023233

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