Cargando…
Prolonged-release melatonin for insomnia – an open-label long-term study of efficacy, safety, and withdrawal
BACKGROUND: Prolonged-release melatonin (PRM) 2 mg is indicated for insomnia in patients aged 55 years and older. A recent double-blind placebo-controlled study demonstrated 6-month efficacy and safety of PRM in insomnia patients aged 18–80 and lack of withdrawal and rebound symptoms upon discontinu...
Autores principales: | Lemoine, Patrick, Garfinkel, Doron, Laudon, Moshe, Nir, Tali, Zisapel, Nava |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3150476/ https://www.ncbi.nlm.nih.gov/pubmed/21845053 http://dx.doi.org/10.2147/TCRM.S23036 |
Ejemplares similares
-
Efficacy and safety of prolonged-release melatonin in insomnia patients with diabetes: a randomized, double-blind, crossover study
por: Garfinkel, Doron, et al.
Publicado: (2011) -
Nightly treatment of primary insomnia with prolonged release melatonin for 6 months: a randomized placebo controlled trial on age and endogenous melatonin as predictors of efficacy and safety
por: Wade, Alan G, et al.
Publicado: (2010) -
Efficacy and safety of prolonged-release melatonin for insomnia in middle-aged and elderly patients with hypertension: a combined analysis of controlled clinical trials
por: Lemoine, Patrick, et al.
Publicado: (2012) -
Long-Term Efficacy and Safety of Pediatric Prolonged-Release Melatonin for Insomnia in Children with Autism Spectrum Disorder
por: Maras, Athanasios, et al.
Publicado: (2018) -
Add-on prolonged-release melatonin for cognitive function and sleep in mild to moderate Alzheimer’s disease: a 6-month, randomized, placebo-controlled, multicenter trial
por: Wade, Alan G, et al.
Publicado: (2014)