Epigenetic memory in induced pluripotent stem cells

Somatic cell nuclear transfer and transcription factor-based reprogramming revert adult cells to an embryonic state, and yield pluripotent stem cells that can generate all tissues. These two reprogramming methods reset genomic methylation, an epigenetic modification of DNA that influences gene expre...

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Detalles Bibliográficos
Autores principales: Kim, K, Doi, A, Wen, B, Ng, K, Zhao, R, Cahan, P, Kim, J, Aryee, MJ, Ji, H, Ehrlich, L, Yabuuchi, A, Takeuchi, A, Cunniff, KC, Hongguang, H, Mckinney-Freeman, S, Naveiras, O, Yoon, TJ, Irizarry, RA, Jung, N, Seita, J, Hanna, J, Murakami, P, Jaenisch, R, Weissleder, R, Orkin, SH, Weissman, IL, Feinberg, AP, Daley, GQ
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3150836/
https://www.ncbi.nlm.nih.gov/pubmed/20644535
http://dx.doi.org/10.1038/nature09342

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