Bcl-2 Inhibits the Innate Immune Response during Early Pathogenesis of Murine Congenital Muscular Dystrophy

Laminin α2 (LAMA2)-deficient congenital muscular dystrophy is a severe, early-onset disease caused by abnormal levels of laminin 211 in the basal lamina leading to muscle weakness, transient inflammation, muscle degeneration and impaired mobility. In a Lama2-deficient mouse model for this disease, a...

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Detalles Bibliográficos
Autores principales: Jeudy, Sheila, Wardrop, Katherine E., Alessi, Amy, Dominov, Janice A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3151242/
https://www.ncbi.nlm.nih.gov/pubmed/21850221
http://dx.doi.org/10.1371/journal.pone.0022369

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