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Reduced Reactivation from Dormancy but Maintained Lineage Choice of Human Mesenchymal Stem Cells with Donor Age

Mesenchymal stem cells (MSC) are promising for cell-based regeneration therapies but up to date it is still controversial whether their function is maintained throughout ageing. Aim of this study was to address whether frequency, activation in vitro, replicative function, and in vitro lineage choice...

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Detalles Bibliográficos
Autores principales: Dexheimer, Verena, Mueller, Sebastian, Braatz, Frank, Richter, Wiltrud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3151268/
https://www.ncbi.nlm.nih.gov/pubmed/21850247
http://dx.doi.org/10.1371/journal.pone.0022980