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Design Considerations for Massively Parallel Sequencing Studies of Complex Human Disease

Massively Parallel Sequencing (MPS) allows sequencing of entire exomes and genomes to now be done at reasonable cost, and its utility for identifying genes responsible for rare Mendelian disorders has been demonstrated. However, for a complex disease, study designs need to accommodate substantial de...

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Detalles Bibliográficos
Autores principales:	Feng, Bing-Jian, Tavtigian, Sean V., Southey, Melissa C., Goldgar, David E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3151293/ https://www.ncbi.nlm.nih.gov/pubmed/21850262 http://dx.doi.org/10.1371/journal.pone.0023221

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