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Taylor Dispersion Analysis Compared to Dynamic Light Scattering for the Size Analysis of Therapeutic Peptides and Proteins and Their Aggregates

PURPOSE: To evaluate Taylor dispersion analysis (TDA) as a novel method for determination of hydrodynamic radius of therapeutic peptides and proteins in non-stressed and stressed formulations and to compare it with dynamic light scattering (DLS). METHODS: The hydrodynamic radius of oxytocin, bovine...

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Detalles Bibliográficos
Autores principales:	Hawe, Andrea, Hulse, Wendy L., Jiskoot, Wim, Forbes, Robert T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2011
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3151397/ https://www.ncbi.nlm.nih.gov/pubmed/21560019 http://dx.doi.org/10.1007/s11095-011-0460-3

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