Methyl 2-acetamido-2-(4-hy­droxy-2-methyl-1,3-dioxo-1,2,3,4-tetra­hydro­isoquinolin-4-yl)-4-methyl­penta­noate

In the isoquinoline ring system of the title mol­ecule, C(19)H(24)N(2)O(6), the N-heterocyclic ring is in a half-boat conformation. The mol­ecular structure is stabilized by an intra­molecular O—H⋯O hydrogen bond, which generates an S(7) ring motif. In the crystal, mol­ecules are linked via inter­mo...

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Detalles Bibliográficos
Autores principales: Fun, Hoong-Kun, Quah, Ching Kheng, Xu, Kai, Zhang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3151770/
https://www.ncbi.nlm.nih.gov/pubmed/21837104
http://dx.doi.org/10.1107/S1600536811022999
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author Fun, Hoong-Kun
Quah, Ching Kheng
Xu, Kai
Zhang, Yan
author_facet Fun, Hoong-Kun
Quah, Ching Kheng
Xu, Kai
Zhang, Yan
author_sort Fun, Hoong-Kun
collection PubMed
description In the isoquinoline ring system of the title mol­ecule, C(19)H(24)N(2)O(6), the N-heterocyclic ring is in a half-boat conformation. The mol­ecular structure is stabilized by an intra­molecular O—H⋯O hydrogen bond, which generates an S(7) ring motif. In the crystal, mol­ecules are linked via inter­molecular bifurcated N—H⋯(O,O) and weak C—H⋯O hydrogen bonds into a three-dimensional network.
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spelling pubmed-31517702011-08-11 Methyl 2-acetamido-2-(4-hy­droxy-2-methyl-1,3-dioxo-1,2,3,4-tetra­hydro­isoquinolin-4-yl)-4-methyl­penta­noate Fun, Hoong-Kun Quah, Ching Kheng Xu, Kai Zhang, Yan Acta Crystallogr Sect E Struct Rep Online Organic Papers In the isoquinoline ring system of the title mol­ecule, C(19)H(24)N(2)O(6), the N-heterocyclic ring is in a half-boat conformation. The mol­ecular structure is stabilized by an intra­molecular O—H⋯O hydrogen bond, which generates an S(7) ring motif. In the crystal, mol­ecules are linked via inter­molecular bifurcated N—H⋯(O,O) and weak C—H⋯O hydrogen bonds into a three-dimensional network. International Union of Crystallography 2011-06-18 /pmc/articles/PMC3151770/ /pubmed/21837104 http://dx.doi.org/10.1107/S1600536811022999 Text en © Fun et al. 2011 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Fun, Hoong-Kun
Quah, Ching Kheng
Xu, Kai
Zhang, Yan
Methyl 2-acetamido-2-(4-hy­droxy-2-methyl-1,3-dioxo-1,2,3,4-tetra­hydro­isoquinolin-4-yl)-4-methyl­penta­noate
title Methyl 2-acetamido-2-(4-hy­droxy-2-methyl-1,3-dioxo-1,2,3,4-tetra­hydro­isoquinolin-4-yl)-4-methyl­penta­noate
title_full Methyl 2-acetamido-2-(4-hy­droxy-2-methyl-1,3-dioxo-1,2,3,4-tetra­hydro­isoquinolin-4-yl)-4-methyl­penta­noate
title_fullStr Methyl 2-acetamido-2-(4-hy­droxy-2-methyl-1,3-dioxo-1,2,3,4-tetra­hydro­isoquinolin-4-yl)-4-methyl­penta­noate
title_full_unstemmed Methyl 2-acetamido-2-(4-hy­droxy-2-methyl-1,3-dioxo-1,2,3,4-tetra­hydro­isoquinolin-4-yl)-4-methyl­penta­noate
title_short Methyl 2-acetamido-2-(4-hy­droxy-2-methyl-1,3-dioxo-1,2,3,4-tetra­hydro­isoquinolin-4-yl)-4-methyl­penta­noate
title_sort methyl 2-acetamido-2-(4-hy­droxy-2-methyl-1,3-dioxo-1,2,3,4-tetra­hydro­isoquinolin-4-yl)-4-methyl­penta­noate
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3151770/
https://www.ncbi.nlm.nih.gov/pubmed/21837104
http://dx.doi.org/10.1107/S1600536811022999
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AT zhangyan methyl2acetamido24hydroxy2methyl13dioxo1234tetrahydroisoquinolin4yl4methylpentanoate

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