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(4-Nitrophenyl)(1,2,3,9-tetrahydro­pyrrolo[2,1-b]quinazolin-3-yl)methanol monohydrate

In the crystal structure of the title compound, C(18)H(17)N(3)O(3)·H(2)O, the mol­ecules are linked by O—H⋯O and O—H⋯N hydrogen bonds, resulting in a chain along the a axis. The crystal structure is stabilized by weak inter­molecular C—H⋯π (ring) hydrogen bonds and aromatic π⋯π stacking inter­action...

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Autores principales: Elmuradov, Burkhon Zh., Makhmadiyarova, Charoskhon E., Turgunov, Kambarali K., Tashkhodjaev, Bakhodir, Shakhidoyatov, Khusnutdin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3151778/
https://www.ncbi.nlm.nih.gov/pubmed/21837078
http://dx.doi.org/10.1107/S1600536811021775
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author Elmuradov, Burkhon Zh.
Makhmadiyarova, Charoskhon E.
Turgunov, Kambarali K.
Tashkhodjaev, Bakhodir
Shakhidoyatov, Khusnutdin M.
author_facet Elmuradov, Burkhon Zh.
Makhmadiyarova, Charoskhon E.
Turgunov, Kambarali K.
Tashkhodjaev, Bakhodir
Shakhidoyatov, Khusnutdin M.
author_sort Elmuradov, Burkhon Zh.
collection PubMed
description In the crystal structure of the title compound, C(18)H(17)N(3)O(3)·H(2)O, the mol­ecules are linked by O—H⋯O and O—H⋯N hydrogen bonds, resulting in a chain along the a axis. The crystal structure is stabilized by weak inter­molecular C—H⋯π (ring) hydrogen bonds and aromatic π⋯π stacking inter­actions [centroid–centroid distance = 3.902 (1) Å] between the pyrimidino rings of the quinazoline system. The tricyclic quinazoline fragment is almost planar (rms deviation = 0.0139 Å) with the two methylene C atoms of the pyrrolo ring deviating by 0.148 (2) and −0.081 (3) Å from the plane through the other atoms. The 4-nitrophenyl ring makes a dihedral angle of 12.55 (7)° with the tricyclic ring system.
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spelling pubmed-31517782011-08-11 (4-Nitrophenyl)(1,2,3,9-tetrahydro­pyrrolo[2,1-b]quinazolin-3-yl)methanol monohydrate Elmuradov, Burkhon Zh. Makhmadiyarova, Charoskhon E. Turgunov, Kambarali K. Tashkhodjaev, Bakhodir Shakhidoyatov, Khusnutdin M. Acta Crystallogr Sect E Struct Rep Online Organic Papers In the crystal structure of the title compound, C(18)H(17)N(3)O(3)·H(2)O, the mol­ecules are linked by O—H⋯O and O—H⋯N hydrogen bonds, resulting in a chain along the a axis. The crystal structure is stabilized by weak inter­molecular C—H⋯π (ring) hydrogen bonds and aromatic π⋯π stacking inter­actions [centroid–centroid distance = 3.902 (1) Å] between the pyrimidino rings of the quinazoline system. The tricyclic quinazoline fragment is almost planar (rms deviation = 0.0139 Å) with the two methylene C atoms of the pyrrolo ring deviating by 0.148 (2) and −0.081 (3) Å from the plane through the other atoms. The 4-nitrophenyl ring makes a dihedral angle of 12.55 (7)° with the tricyclic ring system. International Union of Crystallography 2011-06-18 /pmc/articles/PMC3151778/ /pubmed/21837078 http://dx.doi.org/10.1107/S1600536811021775 Text en © Elmuradov et al. 2011 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Elmuradov, Burkhon Zh.
Makhmadiyarova, Charoskhon E.
Turgunov, Kambarali K.
Tashkhodjaev, Bakhodir
Shakhidoyatov, Khusnutdin M.
(4-Nitrophenyl)(1,2,3,9-tetrahydro­pyrrolo[2,1-b]quinazolin-3-yl)methanol monohydrate
title (4-Nitrophenyl)(1,2,3,9-tetrahydro­pyrrolo[2,1-b]quinazolin-3-yl)methanol monohydrate
title_full (4-Nitrophenyl)(1,2,3,9-tetrahydro­pyrrolo[2,1-b]quinazolin-3-yl)methanol monohydrate
title_fullStr (4-Nitrophenyl)(1,2,3,9-tetrahydro­pyrrolo[2,1-b]quinazolin-3-yl)methanol monohydrate
title_full_unstemmed (4-Nitrophenyl)(1,2,3,9-tetrahydro­pyrrolo[2,1-b]quinazolin-3-yl)methanol monohydrate
title_short (4-Nitrophenyl)(1,2,3,9-tetrahydro­pyrrolo[2,1-b]quinazolin-3-yl)methanol monohydrate
title_sort (4-nitrophenyl)(1,2,3,9-tetrahydro­pyrrolo[2,1-b]quinazolin-3-yl)methanol monohydrate
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3151778/
https://www.ncbi.nlm.nih.gov/pubmed/21837078
http://dx.doi.org/10.1107/S1600536811021775
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