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[(2S,5R)-1-Methyl-5-phenyl­pyrrolidin-2-yl]diphenyl­methanol

In the title compound, C(24)H(25)NO, the phenyl and diphenyl­methanol substituents are syn to each other. The pyrrolidine ring has an envelope conformation with the flap atom being the C atom bearing the phenyl substituent. The hy­droxy group forms an intra­molecular hydrogen bond with the pyrrolidi...

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Autores principales: Zukerman-Schpector, Julio, Venturini Moro, Angélica, Lüdtke, Diogo S., Correia, Carlos Roque D., Tiekink, Edward R. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3151780/
https://www.ncbi.nlm.nih.gov/pubmed/21837179
http://dx.doi.org/10.1107/S1600536811023403
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author Zukerman-Schpector, Julio
Venturini Moro, Angélica
Lüdtke, Diogo S.
Correia, Carlos Roque D.
Tiekink, Edward R. T.
author_facet Zukerman-Schpector, Julio
Venturini Moro, Angélica
Lüdtke, Diogo S.
Correia, Carlos Roque D.
Tiekink, Edward R. T.
author_sort Zukerman-Schpector, Julio
collection PubMed
description In the title compound, C(24)H(25)NO, the phenyl and diphenyl­methanol substituents are syn to each other. The pyrrolidine ring has an envelope conformation with the flap atom being the C atom bearing the phenyl substituent. The hy­droxy group forms an intra­molecular hydrogen bond with the pyrrolidine N atom, and the phenyl rings lie to same side of the mol­ecule. The crystal packing features C—H⋯π inter­actions. Two slightly displaced co-planar orientations were found for one of the phenyl rings; the major component had a site-occupancy factor of 0.782 (15).
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spelling pubmed-31517802011-08-11 [(2S,5R)-1-Methyl-5-phenyl­pyrrolidin-2-yl]diphenyl­methanol Zukerman-Schpector, Julio Venturini Moro, Angélica Lüdtke, Diogo S. Correia, Carlos Roque D. Tiekink, Edward R. T. Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(24)H(25)NO, the phenyl and diphenyl­methanol substituents are syn to each other. The pyrrolidine ring has an envelope conformation with the flap atom being the C atom bearing the phenyl substituent. The hy­droxy group forms an intra­molecular hydrogen bond with the pyrrolidine N atom, and the phenyl rings lie to same side of the mol­ecule. The crystal packing features C—H⋯π inter­actions. Two slightly displaced co-planar orientations were found for one of the phenyl rings; the major component had a site-occupancy factor of 0.782 (15). International Union of Crystallography 2011-06-25 /pmc/articles/PMC3151780/ /pubmed/21837179 http://dx.doi.org/10.1107/S1600536811023403 Text en © Zukerman-Schpector et al. 2011 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Zukerman-Schpector, Julio
Venturini Moro, Angélica
Lüdtke, Diogo S.
Correia, Carlos Roque D.
Tiekink, Edward R. T.
[(2S,5R)-1-Methyl-5-phenyl­pyrrolidin-2-yl]diphenyl­methanol
title [(2S,5R)-1-Methyl-5-phenyl­pyrrolidin-2-yl]diphenyl­methanol
title_full [(2S,5R)-1-Methyl-5-phenyl­pyrrolidin-2-yl]diphenyl­methanol
title_fullStr [(2S,5R)-1-Methyl-5-phenyl­pyrrolidin-2-yl]diphenyl­methanol
title_full_unstemmed [(2S,5R)-1-Methyl-5-phenyl­pyrrolidin-2-yl]diphenyl­methanol
title_short [(2S,5R)-1-Methyl-5-phenyl­pyrrolidin-2-yl]diphenyl­methanol
title_sort [(2s,5r)-1-methyl-5-phenyl­pyrrolidin-2-yl]diphenyl­methanol
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3151780/
https://www.ncbi.nlm.nih.gov/pubmed/21837179
http://dx.doi.org/10.1107/S1600536811023403
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