Cargando…
[(2S,5R)-1-Methyl-5-phenylpyrrolidin-2-yl]diphenylmethanol
In the title compound, C(24)H(25)NO, the phenyl and diphenylmethanol substituents are syn to each other. The pyrrolidine ring has an envelope conformation with the flap atom being the C atom bearing the phenyl substituent. The hydroxy group forms an intramolecular hydrogen bond with the pyrrolidi...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3151780/ https://www.ncbi.nlm.nih.gov/pubmed/21837179 http://dx.doi.org/10.1107/S1600536811023403 |
_version_ | 1782209654150922240 |
---|---|
author | Zukerman-Schpector, Julio Venturini Moro, Angélica Lüdtke, Diogo S. Correia, Carlos Roque D. Tiekink, Edward R. T. |
author_facet | Zukerman-Schpector, Julio Venturini Moro, Angélica Lüdtke, Diogo S. Correia, Carlos Roque D. Tiekink, Edward R. T. |
author_sort | Zukerman-Schpector, Julio |
collection | PubMed |
description | In the title compound, C(24)H(25)NO, the phenyl and diphenylmethanol substituents are syn to each other. The pyrrolidine ring has an envelope conformation with the flap atom being the C atom bearing the phenyl substituent. The hydroxy group forms an intramolecular hydrogen bond with the pyrrolidine N atom, and the phenyl rings lie to same side of the molecule. The crystal packing features C—H⋯π interactions. Two slightly displaced co-planar orientations were found for one of the phenyl rings; the major component had a site-occupancy factor of 0.782 (15). |
format | Online Article Text |
id | pubmed-3151780 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | International Union of Crystallography |
record_format | MEDLINE/PubMed |
spelling | pubmed-31517802011-08-11 [(2S,5R)-1-Methyl-5-phenylpyrrolidin-2-yl]diphenylmethanol Zukerman-Schpector, Julio Venturini Moro, Angélica Lüdtke, Diogo S. Correia, Carlos Roque D. Tiekink, Edward R. T. Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(24)H(25)NO, the phenyl and diphenylmethanol substituents are syn to each other. The pyrrolidine ring has an envelope conformation with the flap atom being the C atom bearing the phenyl substituent. The hydroxy group forms an intramolecular hydrogen bond with the pyrrolidine N atom, and the phenyl rings lie to same side of the molecule. The crystal packing features C—H⋯π interactions. Two slightly displaced co-planar orientations were found for one of the phenyl rings; the major component had a site-occupancy factor of 0.782 (15). International Union of Crystallography 2011-06-25 /pmc/articles/PMC3151780/ /pubmed/21837179 http://dx.doi.org/10.1107/S1600536811023403 Text en © Zukerman-Schpector et al. 2011 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
spellingShingle | Organic Papers Zukerman-Schpector, Julio Venturini Moro, Angélica Lüdtke, Diogo S. Correia, Carlos Roque D. Tiekink, Edward R. T. [(2S,5R)-1-Methyl-5-phenylpyrrolidin-2-yl]diphenylmethanol |
title | [(2S,5R)-1-Methyl-5-phenylpyrrolidin-2-yl]diphenylmethanol |
title_full | [(2S,5R)-1-Methyl-5-phenylpyrrolidin-2-yl]diphenylmethanol |
title_fullStr | [(2S,5R)-1-Methyl-5-phenylpyrrolidin-2-yl]diphenylmethanol |
title_full_unstemmed | [(2S,5R)-1-Methyl-5-phenylpyrrolidin-2-yl]diphenylmethanol |
title_short | [(2S,5R)-1-Methyl-5-phenylpyrrolidin-2-yl]diphenylmethanol |
title_sort | [(2s,5r)-1-methyl-5-phenylpyrrolidin-2-yl]diphenylmethanol |
topic | Organic Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3151780/ https://www.ncbi.nlm.nih.gov/pubmed/21837179 http://dx.doi.org/10.1107/S1600536811023403 |
work_keys_str_mv | AT zukermanschpectorjulio 2s5r1methyl5phenylpyrrolidin2yldiphenylmethanol AT venturinimoroangelica 2s5r1methyl5phenylpyrrolidin2yldiphenylmethanol AT ludtkediogos 2s5r1methyl5phenylpyrrolidin2yldiphenylmethanol AT correiacarlosroqued 2s5r1methyl5phenylpyrrolidin2yldiphenylmethanol AT tiekinkedwardrt 2s5r1methyl5phenylpyrrolidin2yldiphenylmethanol |