Cargando…

7-Methyl-5,6,7,8-tetra­hydro-1-benzo­thieno[2,3-d]pyrimidin-4-amine

In the title compound, C(11)H(13)N(3)S, two of the C atoms of the cyclo­hexene ring and the methyl group attached to it are disordered over two sets of sites in a 0.544 (2):0.456 (2) ratio. The benzothiene and pyrimidine rings are almost coplanar with an angular tilt of 2.371 (9)° between them. The...

Descripción completa

Detalles Bibliográficos
Autores principales: Ziaulla, Mohamed, Banu, Afshan, Begum, Noor Shahina, Panchamukhi, Shridhar I., Khazi, I. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3151862/
https://www.ncbi.nlm.nih.gov/pubmed/21837042
http://dx.doi.org/10.1107/S1600536811021155
Descripción
Sumario:In the title compound, C(11)H(13)N(3)S, two of the C atoms of the cyclo­hexene ring and the methyl group attached to it are disordered over two sets of sites in a 0.544 (2):0.456 (2) ratio. The benzothiene and pyrimidine rings are almost coplanar with an angular tilt of 2.371 (9)° between them. The thio­phene ring is essentially planar (r.m.s. deviation 0.05 Å), while the cyclo­hexene ring in both the major- and minor-occupancy conformers adopts a half-chair conformation. In the crystal structure, pairs of intermolecular N—H⋯N hydrogen bonds involving the amino groups result in centrosymmetric head-to-head dimers about inversion centres, corresponding to an R (2) (2)(8) graph-set motif. Further, N—H⋯N hydrogen bonding generates a two-dimensional hydrogen-bonded network perpendicular to the ac plane and running along the diagonal of the ac plane.