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5′-Methyl-4′-oxo-7′-phenyl-3′,4′-dihydro-1′H-spiro[cyclohexane-1,2′-quinazoline]-8′-carbonitrile
The title compound, C(21)H(21)N(3)O, was obtained by cyclocondensation of 3-amino-5-methyl-[1,1′-biphenyl]-2,4-dicarbonitrile with cyclohexanone. The six-membered 1,3-diaza ring assumes an envelope conformation [with the flap atom displaced by 0.511 (7) Å from the plane through the other ring...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
International Union of Crystallography
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152013/ https://www.ncbi.nlm.nih.gov/pubmed/21837071 http://dx.doi.org/10.1107/S160053681102188X |
| _version_ | 1782209707714281472 |
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| author | Tang, Jianhong Shi, Daxin Yan, Liupan Liu, Xuan Li, Jiarong |
| author_facet | Tang, Jianhong Shi, Daxin Yan, Liupan Liu, Xuan Li, Jiarong |
| author_sort | Tang, Jianhong |
| collection | PubMed |
| description | The title compound, C(21)H(21)N(3)O, was obtained by cyclocondensation of 3-amino-5-methyl-[1,1′-biphenyl]-2,4-dicarbonitrile with cyclohexanone. The six-membered 1,3-diaza ring assumes an envelope conformation [with the flap atom displaced by 0.511 (7) Å from the plane through the other ring atoms] and the cyclohexane ring displays a chair conformation. The dihedral angle between the aromatic rings is 42.61 (7)°.In the crystal, the molecules form hydrogen-bonded bands along [011]. |
| format | Online Article Text |
| id | pubmed-3152013 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2011 |
| publisher | International Union of Crystallography |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-31520132011-08-11 5′-Methyl-4′-oxo-7′-phenyl-3′,4′-dihydro-1′H-spiro[cyclohexane-1,2′-quinazoline]-8′-carbonitrile Tang, Jianhong Shi, Daxin Yan, Liupan Liu, Xuan Li, Jiarong Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(21)H(21)N(3)O, was obtained by cyclocondensation of 3-amino-5-methyl-[1,1′-biphenyl]-2,4-dicarbonitrile with cyclohexanone. The six-membered 1,3-diaza ring assumes an envelope conformation [with the flap atom displaced by 0.511 (7) Å from the plane through the other ring atoms] and the cyclohexane ring displays a chair conformation. The dihedral angle between the aromatic rings is 42.61 (7)°.In the crystal, the molecules form hydrogen-bonded bands along [011]. International Union of Crystallography 2011-06-18 /pmc/articles/PMC3152013/ /pubmed/21837071 http://dx.doi.org/10.1107/S160053681102188X Text en © Tang et al. 2011 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
| spellingShingle | Organic Papers Tang, Jianhong Shi, Daxin Yan, Liupan Liu, Xuan Li, Jiarong 5′-Methyl-4′-oxo-7′-phenyl-3′,4′-dihydro-1′H-spiro[cyclohexane-1,2′-quinazoline]-8′-carbonitrile |
| title | 5′-Methyl-4′-oxo-7′-phenyl-3′,4′-dihydro-1′H-spiro[cyclohexane-1,2′-quinazoline]-8′-carbonitrile |
| title_full | 5′-Methyl-4′-oxo-7′-phenyl-3′,4′-dihydro-1′H-spiro[cyclohexane-1,2′-quinazoline]-8′-carbonitrile |
| title_fullStr | 5′-Methyl-4′-oxo-7′-phenyl-3′,4′-dihydro-1′H-spiro[cyclohexane-1,2′-quinazoline]-8′-carbonitrile |
| title_full_unstemmed | 5′-Methyl-4′-oxo-7′-phenyl-3′,4′-dihydro-1′H-spiro[cyclohexane-1,2′-quinazoline]-8′-carbonitrile |
| title_short | 5′-Methyl-4′-oxo-7′-phenyl-3′,4′-dihydro-1′H-spiro[cyclohexane-1,2′-quinazoline]-8′-carbonitrile |
| title_sort | 5′-methyl-4′-oxo-7′-phenyl-3′,4′-dihydro-1′h-spiro[cyclohexane-1,2′-quinazoline]-8′-carbonitrile |
| topic | Organic Papers |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152013/ https://www.ncbi.nlm.nih.gov/pubmed/21837071 http://dx.doi.org/10.1107/S160053681102188X |
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