Ethyl 2-[1,3-dioxo-6-(piperidin-1-yl)-2,3-dihydro-1H-benz[de]isoquinolin-2-yl]acetate

In the title compound, C(21)H(22)N(2)O(4), the naphthalimide unit is almost planar (r.m.s. deviation = 0.081Å). The carboximide N atom and the five C atoms of the eth­oxy­carbonyl­methyl substituent also lie close to a common plane (r.m.s. deviation = 0.119Å), which subtends an angle of 71.06 (8)° t...

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Autores principales: Xia, Song, Zheng, Chun-Ling, He, Fei-Fei, Shi, Ya-Bin, Wang, Hai-Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152026/
https://www.ncbi.nlm.nih.gov/pubmed/21837109
http://dx.doi.org/10.1107/S1600536811022707
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author Xia, Song
Zheng, Chun-Ling
He, Fei-Fei
Shi, Ya-Bin
Wang, Hai-Bo
author_facet Xia, Song
Zheng, Chun-Ling
He, Fei-Fei
Shi, Ya-Bin
Wang, Hai-Bo
author_sort Xia, Song
collection PubMed
description In the title compound, C(21)H(22)N(2)O(4), the naphthalimide unit is almost planar (r.m.s. deviation = 0.081Å). The carboximide N atom and the five C atoms of the eth­oxy­carbonyl­methyl substituent also lie close to a common plane (r.m.s. deviation = 0.119Å), which subtends an angle of 71.06 (8)° to the naphthalamide plane. The piperidine ring adopts a chair conformation. In the crystal, inter­molecular C—H⋯O hydrogen bonds link the mol­ecules into zigzag chains along the a axis.
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spelling pubmed-31520262011-08-11 Ethyl 2-[1,3-dioxo-6-(piperidin-1-yl)-2,3-dihydro-1H-benz[de]isoquinolin-2-yl]acetate Xia, Song Zheng, Chun-Ling He, Fei-Fei Shi, Ya-Bin Wang, Hai-Bo Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(21)H(22)N(2)O(4), the naphthalimide unit is almost planar (r.m.s. deviation = 0.081Å). The carboximide N atom and the five C atoms of the eth­oxy­carbonyl­methyl substituent also lie close to a common plane (r.m.s. deviation = 0.119Å), which subtends an angle of 71.06 (8)° to the naphthalamide plane. The piperidine ring adopts a chair conformation. In the crystal, inter­molecular C—H⋯O hydrogen bonds link the mol­ecules into zigzag chains along the a axis. International Union of Crystallography 2011-06-18 /pmc/articles/PMC3152026/ /pubmed/21837109 http://dx.doi.org/10.1107/S1600536811022707 Text en © Xia et al. 2011 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Xia, Song
Zheng, Chun-Ling
He, Fei-Fei
Shi, Ya-Bin
Wang, Hai-Bo
Ethyl 2-[1,3-dioxo-6-(piperidin-1-yl)-2,3-dihydro-1H-benz[de]isoquinolin-2-yl]acetate
title Ethyl 2-[1,3-dioxo-6-(piperidin-1-yl)-2,3-dihydro-1H-benz[de]isoquinolin-2-yl]acetate
title_full Ethyl 2-[1,3-dioxo-6-(piperidin-1-yl)-2,3-dihydro-1H-benz[de]isoquinolin-2-yl]acetate
title_fullStr Ethyl 2-[1,3-dioxo-6-(piperidin-1-yl)-2,3-dihydro-1H-benz[de]isoquinolin-2-yl]acetate
title_full_unstemmed Ethyl 2-[1,3-dioxo-6-(piperidin-1-yl)-2,3-dihydro-1H-benz[de]isoquinolin-2-yl]acetate
title_short Ethyl 2-[1,3-dioxo-6-(piperidin-1-yl)-2,3-dihydro-1H-benz[de]isoquinolin-2-yl]acetate
title_sort ethyl 2-[1,3-dioxo-6-(piperidin-1-yl)-2,3-dihydro-1h-benz[de]isoquinolin-2-yl]acetate
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152026/
https://www.ncbi.nlm.nih.gov/pubmed/21837109
http://dx.doi.org/10.1107/S1600536811022707
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