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4-(5,6-Dihydro­benzimidazo[1,2-c]quinazolin-6-yl)benzene-1,3-diol dimethyl sulfoxide monosolvate

In the title solvated benzimidazole compound, C(20)H(15)N(3)O(2)·C(2)H(6)OS, both the benzimidazole fused-ring system and the complete dimethyl sulfoxide solvent mol­ecule are disordered over two sets of sites, in 0.750 (5):0.250 (5) and 0.882 (4):0.118 (4) ratios, respectively. The conformation of...

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Autores principales: Eltayeb, Naser Eltaher, Teoh, Siang Guan, Yeap, Chin Sing, Fun, Hoong-Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152048/
https://www.ncbi.nlm.nih.gov/pubmed/21837112
http://dx.doi.org/10.1107/S160053681102304X
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author Eltayeb, Naser Eltaher
Teoh, Siang Guan
Yeap, Chin Sing
Fun, Hoong-Kun
author_facet Eltayeb, Naser Eltaher
Teoh, Siang Guan
Yeap, Chin Sing
Fun, Hoong-Kun
author_sort Eltayeb, Naser Eltaher
collection PubMed
description In the title solvated benzimidazole compound, C(20)H(15)N(3)O(2)·C(2)H(6)OS, both the benzimidazole fused-ring system and the complete dimethyl sulfoxide solvent mol­ecule are disordered over two sets of sites, in 0.750 (5):0.250 (5) and 0.882 (4):0.118 (4) ratios, respectively. The conformation of the pyrimidine ring is close to a half-chair for the major disorder component, whereas for the minor component it is close to a boat. The dihy­droxy­phenyl ring is almost perpendicular to the mean plane of the benzimidazole ring [dihedral angle = 87.3 (2)° for the major disorder component and 88.3 (5)° for the minor disorder component]. In the crystal, mol­ecules are linked into layers parallel to (110) by O—H⋯N and C—H⋯O hydrogen bonds. A bifurcated O—H⋯(O,S) bond links the benzimidazole and solvent mol­ecules.
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spelling pubmed-31520482011-08-11 4-(5,6-Dihydro­benzimidazo[1,2-c]quinazolin-6-yl)benzene-1,3-diol dimethyl sulfoxide monosolvate Eltayeb, Naser Eltaher Teoh, Siang Guan Yeap, Chin Sing Fun, Hoong-Kun Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title solvated benzimidazole compound, C(20)H(15)N(3)O(2)·C(2)H(6)OS, both the benzimidazole fused-ring system and the complete dimethyl sulfoxide solvent mol­ecule are disordered over two sets of sites, in 0.750 (5):0.250 (5) and 0.882 (4):0.118 (4) ratios, respectively. The conformation of the pyrimidine ring is close to a half-chair for the major disorder component, whereas for the minor component it is close to a boat. The dihy­droxy­phenyl ring is almost perpendicular to the mean plane of the benzimidazole ring [dihedral angle = 87.3 (2)° for the major disorder component and 88.3 (5)° for the minor disorder component]. In the crystal, mol­ecules are linked into layers parallel to (110) by O—H⋯N and C—H⋯O hydrogen bonds. A bifurcated O—H⋯(O,S) bond links the benzimidazole and solvent mol­ecules. International Union of Crystallography 2011-06-18 /pmc/articles/PMC3152048/ /pubmed/21837112 http://dx.doi.org/10.1107/S160053681102304X Text en © Eltayeb et al. 2011 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Eltayeb, Naser Eltaher
Teoh, Siang Guan
Yeap, Chin Sing
Fun, Hoong-Kun
4-(5,6-Dihydro­benzimidazo[1,2-c]quinazolin-6-yl)benzene-1,3-diol dimethyl sulfoxide monosolvate
title 4-(5,6-Dihydro­benzimidazo[1,2-c]quinazolin-6-yl)benzene-1,3-diol dimethyl sulfoxide monosolvate
title_full 4-(5,6-Dihydro­benzimidazo[1,2-c]quinazolin-6-yl)benzene-1,3-diol dimethyl sulfoxide monosolvate
title_fullStr 4-(5,6-Dihydro­benzimidazo[1,2-c]quinazolin-6-yl)benzene-1,3-diol dimethyl sulfoxide monosolvate
title_full_unstemmed 4-(5,6-Dihydro­benzimidazo[1,2-c]quinazolin-6-yl)benzene-1,3-diol dimethyl sulfoxide monosolvate
title_short 4-(5,6-Dihydro­benzimidazo[1,2-c]quinazolin-6-yl)benzene-1,3-diol dimethyl sulfoxide monosolvate
title_sort 4-(5,6-dihydro­benzimidazo[1,2-c]quinazolin-6-yl)benzene-1,3-diol dimethyl sulfoxide monosolvate
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152048/
https://www.ncbi.nlm.nih.gov/pubmed/21837112
http://dx.doi.org/10.1107/S160053681102304X
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