Intracellular Serine Protease Inhibitor SERPINB4 Inhibits Granzyme M-Induced Cell Death

Granzyme-mediated cell death is the major pathway for cytotoxic lymphocytes to kill virus-infected and tumor cells. In humans, five different granzymes (i.e. GrA, GrB, GrH, GrK, and GrM) are known that all induce cell death. Expression of intracellular serine protease inhibitors (serpins) is one of...

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Detalles Bibliográficos
Autores principales: de Koning, Pieter J. A., Kummer, J. Alain, de Poot, Stefanie A. H., Quadir, Razi, Broekhuizen, Roel, McGettrick, Anne F., Higgins, Wayne J., Devreese, Bart, Worrall, D. Margaret, Bovenschen, Niels
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152296/
https://www.ncbi.nlm.nih.gov/pubmed/21857942
http://dx.doi.org/10.1371/journal.pone.0022645

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