Differential usage of transcriptional start sites and polyadenylation sites in FMR1 premutation alleles(†)

5′- and 3′-untranslated regions (UTRs) are important regulators of gene expression and play key roles in disease progression and susceptibility. The 5′-UTR of the fragile X mental retardation 1 (FMR1) gene contains a CGG repeat element that is expanded (>200 CGG repeats; full mutation) and methyl...

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Detalles Bibliográficos
Autores principales: Tassone, Flora, De Rubeis, Silvia, Carosi, Chiara, La Fata, Giorgio, Serpa, Gisele, Raske, Christopher, Willemsen, Rob, Hagerman, Paul J., Bagni, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152321/
https://www.ncbi.nlm.nih.gov/pubmed/21478165
http://dx.doi.org/10.1093/nar/gkr100

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