Gcn4 misregulation reveals a direct role for the evolutionary conserved EKC/KEOPS in the t(6)A modification of tRNAs

The EKC/KEOPS complex is universally conserved in Archaea and Eukarya and has been implicated in several cellular processes, including transcription, telomere homeostasis and genomic instability. However, the molecular function of the complex has remained elusive so far. We analyzed the transcriptom...

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Detalles Bibliográficos
Autores principales: Daugeron, Marie-Claire, Lenstra, Tineke L., Frizzarin, Martina, El Yacoubi, Basma, Liu, Xipeng, Baudin-Baillieu, Agnès, Lijnzaad, Philip, Decourty, Laurence, Saveanu, Cosmin, Jacquier, Alain, Holstege, Frank C. P., de Crécy-Lagard, Valérie, van Tilbeurgh, Herman, Libri, Domenico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152333/
https://www.ncbi.nlm.nih.gov/pubmed/21459853
http://dx.doi.org/10.1093/nar/gkr178

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