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The relative efficiency of homology-directed repair has distinct effects on proper anaphase chromosome separation

Homology-directed repair (HDR) is essential to limit mutagenesis, chromosomal instability (CIN) and tumorigenesis. We have characterized the consequences of HDR deficiency on anaphase, using markers for incomplete chromosome separation: DAPI-bridges and Ultra-fine bridges (UFBs). We show that multip...

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Detalles Bibliográficos
Autores principales:	Laulier, Corentin, Cheng, Anita, Stark, Jeremy M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2011
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152340/ https://www.ncbi.nlm.nih.gov/pubmed/21459848 http://dx.doi.org/10.1093/nar/gkr187

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