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Zim17/Tim15 links mitochondrial iron–sulfur cluster biosynthesis to nuclear genome stability

Genomic instability is related to a wide-range of human diseases. Here, we show that mitochondrial iron–sulfur cluster biosynthesis is important for the maintenance of nuclear genome stability in Saccharomyces cerevisiae. Cells lacking the mitochondrial chaperone Zim17 (Tim15/Hep1), a component of t...

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Detalles Bibliográficos
Autores principales:	Díaz de la Loza, María del Carmen, Gallardo, Mercedes, García-Rubio, María Luisa, Izquierdo, Alicia, Herrero, Enrique, Aguilera, Andrés, Wellinger, Ralf Erik
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2011
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152343/ https://www.ncbi.nlm.nih.gov/pubmed/21511814 http://dx.doi.org/10.1093/nar/gkr193

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