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Mechanistic analysis of Xenopus EXO1's function in 5′-strand resection at DNA double-strand breaks

The processing of DNA double-strand breaks (DSBs) into 3′ single-stranded tails is the first step of homology-dependent DSB repair. A key player in this process is the highly conserved eukaryotic exonuclease 1 (EXO1), yet its precise mechanism of action has not been rigorously determined. To address...

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Detalles Bibliográficos
Autores principales:	Liao, Shuren, Toczylowski, Thomas, Yan, Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2011
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152354/ https://www.ncbi.nlm.nih.gov/pubmed/21490081 http://dx.doi.org/10.1093/nar/gkr216

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