Distinct patterns of somatic alterations in a lymphoblastoid and a tumor genome derived from the same individual

Although patterns of somatic alterations have been reported for tumor genomes, little is known on how they compare with alterations present in non-tumor genomes. A comparison of the two would be crucial to better characterize the genetic alterations driving tumorigenesis. We sequenced the genomes of...

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Detalles Bibliográficos
Autores principales: Galante, Pedro A. F., Parmigiani, Raphael B., Zhao, Qi, Caballero, Otávia L., de Souza, Jorge E., Navarro, Fábio C. P., Gerber, Alexandra L., Nicolás, Marisa F., Salim, Anna Christina M., Silva, Ana Paula M., Edsall, Lee, Devalle, Sylvie, Almeida, Luiz G., Ye, Zhen, Kuan, Samantha, Pinheiro, Daniel G., Tojal, Israel, Pedigoni, Renato G., de Sousa, Rodrigo G. M. A., Oliveira, Thiago Y. K., de Paula, Marcelo G., Ohno-Machado, Lucila, Kirkness, Ewen F., Levy, Samuel, da Silva, Wilson A., Vasconcelos, Ana Tereza R., Ren, Bing, Zago, Marco Antonio, Strausberg, Robert L., Simpson, Andrew J. G., de Souza, Sandro J., Camargo, Anamaria A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152357/
https://www.ncbi.nlm.nih.gov/pubmed/21493686
http://dx.doi.org/10.1093/nar/gkr221

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