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Auditory cortex mediates the perceptual effects of acoustic temporal expectation
When events occur at predictable instants, anticipation improves performance. Knowledge of event timing modulates motor circuits, improving response speed. By contrast, the neuronal mechanisms underlying changes in sensory perception due to expectation are not well understood. We have developed a no...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152437/ https://www.ncbi.nlm.nih.gov/pubmed/21170056 http://dx.doi.org/10.1038/nn.2688 |
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author | Jaramillo, Santiago Zador, Anthony M. |
author_facet | Jaramillo, Santiago Zador, Anthony M. |
author_sort | Jaramillo, Santiago |
collection | PubMed |
description | When events occur at predictable instants, anticipation improves performance. Knowledge of event timing modulates motor circuits, improving response speed. By contrast, the neuronal mechanisms underlying changes in sensory perception due to expectation are not well understood. We have developed a novel behavioral paradigm for rats in which we manipulated expectations about sound timing. Valid expectations improved both the speed and the accuracy of subjects’ performance, indicating not only improved motor preparedness but also enhanced perception. Single neuron recordings in primary auditory cortex revealed enhanced representation of sounds during periods of heightened expectation. Furthermore, we found that activity in auditory cortex was causally linked to the performance of the task, and that changes in the neuronal representation of sounds predicted performance on a trial-by-trial basis. Our results indicate that changes in neuronal representation as early as primary sensory cortex mediate the perceptual advantage conferred by temporal expectation. |
format | Online Article Text |
id | pubmed-3152437 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
record_format | MEDLINE/PubMed |
spelling | pubmed-31524372011-08-08 Auditory cortex mediates the perceptual effects of acoustic temporal expectation Jaramillo, Santiago Zador, Anthony M. Nat Neurosci Article When events occur at predictable instants, anticipation improves performance. Knowledge of event timing modulates motor circuits, improving response speed. By contrast, the neuronal mechanisms underlying changes in sensory perception due to expectation are not well understood. We have developed a novel behavioral paradigm for rats in which we manipulated expectations about sound timing. Valid expectations improved both the speed and the accuracy of subjects’ performance, indicating not only improved motor preparedness but also enhanced perception. Single neuron recordings in primary auditory cortex revealed enhanced representation of sounds during periods of heightened expectation. Furthermore, we found that activity in auditory cortex was causally linked to the performance of the task, and that changes in the neuronal representation of sounds predicted performance on a trial-by-trial basis. Our results indicate that changes in neuronal representation as early as primary sensory cortex mediate the perceptual advantage conferred by temporal expectation. 2010-12-19 2011-02 /pmc/articles/PMC3152437/ /pubmed/21170056 http://dx.doi.org/10.1038/nn.2688 Text en Users may view, print, copy, download and text and data- mine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use: http://www.nature.com/authors/editorial_policies/license.html#terms |
spellingShingle | Article Jaramillo, Santiago Zador, Anthony M. Auditory cortex mediates the perceptual effects of acoustic temporal expectation |
title | Auditory cortex mediates the perceptual effects of acoustic temporal expectation |
title_full | Auditory cortex mediates the perceptual effects of acoustic temporal expectation |
title_fullStr | Auditory cortex mediates the perceptual effects of acoustic temporal expectation |
title_full_unstemmed | Auditory cortex mediates the perceptual effects of acoustic temporal expectation |
title_short | Auditory cortex mediates the perceptual effects of acoustic temporal expectation |
title_sort | auditory cortex mediates the perceptual effects of acoustic temporal expectation |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152437/ https://www.ncbi.nlm.nih.gov/pubmed/21170056 http://dx.doi.org/10.1038/nn.2688 |
work_keys_str_mv | AT jaramillosantiago auditorycortexmediatestheperceptualeffectsofacoustictemporalexpectation AT zadoranthonym auditorycortexmediatestheperceptualeffectsofacoustictemporalexpectation |