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Effect of silibinin on endothelial dysfunction and ADMA levels in obese diabetic mice
BACKGROUND: Cardiovascular diseases (CVD) in diabetic patients have endothelial dysfunction as a key pathogenetic event. Asymmetric dimethylarginine (ADMA), an endogenous inhibitor of nitric oxide synthase (NOS), plays a pivotal role in endothelial dysfunction. Different natural polyphenols have bee...
Autores principales: | Li Volti, Giovanni, Salomone, Salvatore, Sorrenti, Valeria, Mangiameli, Andrea, Urso, Vincenzo, Siarkos, Ilias, Galvano, Fabio, Salamone, Federico |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152512/ https://www.ncbi.nlm.nih.gov/pubmed/21756303 http://dx.doi.org/10.1186/1475-2840-10-62 |
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