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Exogenous HIV-1 Nef Upsets the IFN-γ-Induced Impairment of Human Intestinal Epithelial Integrity

BACKGROUND: The mucosal tissues play a central role in the transmission of HIV-1 infection as well as in the pathogenesis of AIDS. Despite several clinical studies reported intestinal dysfunction during HIV infection, the mechanisms underlying HIV-induced impairments of mucosal epithelial barrier ar...

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Detalles Bibliográficos
Autores principales: Quaranta, Maria Giovanna, Vincentini, Olimpia, Felli, Cristina, Spadaro, Francesca, Silano, Marco, Moricoli, Diego, Giordani, Luciana, Viora, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152569/
https://www.ncbi.nlm.nih.gov/pubmed/21858117
http://dx.doi.org/10.1371/journal.pone.0023442