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Greatly attenuated experimental autoimmune encephalomyelitis in aquaporin-4 knockout mice

BACKGROUND: The involvement of astrocyte water channel aquaporin-4 (AQP4) in autoimmune diseases of the central nervous system has been suggested following the identification of AQP4 autoantibodies in neuromyelitis optica, an inflammatory demyelinating disease. RESULTS: We investigated the involveme...

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Detalles Bibliográficos
Autores principales: Li, Lihua, Zhang, Hua, Verkman, AS
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152780/
https://www.ncbi.nlm.nih.gov/pubmed/19660138
http://dx.doi.org/10.1186/1471-2202-10-94