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Fingolimod modulates microglial activation to augment markers of remyelination
INTRODUCTION: Microglial activation in multiple sclerosis has been postulated to contribute to long-term neurodegeneration during disease. Fingolimod has been shown to impact on the relapsing remitting phase of disease by modulating autoreactive T-cell egress from lymph organs. In addition, it is br...
Autores principales: | Jackson, Samuel J, Giovannoni, Gavin, Baker, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152910/ https://www.ncbi.nlm.nih.gov/pubmed/21729281 http://dx.doi.org/10.1186/1742-2094-8-76 |
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