Elevated Serum Levels of IGF-1 Are Sufficient to Establish Normal Body Size and Skeletal Properties Even in the Absence of Tissue IGF-1

Use of recombinant insulin-like growth factor 1 (IGF-1) as a treatment for primary IGF-1 deficiency in children has become increasingly common. When untreated, primary IGF-1 deficiency may lead to a range of metabolic disorders, including lipid abnormalities, insulin resistance, and decreased bone d...

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Detalles Bibliográficos
Autores principales: Elis, Sebastien, Courtland, Hayden-William, Wu, Yingjie, Rosen, Clifford J, Sun, Hui, Jepsen, Karl J, Majeska, Robert J, Yakar, Shoshana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2010
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153133/
https://www.ncbi.nlm.nih.gov/pubmed/20200935
http://dx.doi.org/10.1002/jbmr.20

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