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IKKβ Activation Is Sufficient for RANK-Independent Osteoclast Differentiation and Osteolysis
Monocytes differentiate into osteoclasts through stimulation of receptor activator of NF-κB (RANK). Many downstream effectors of RANK play a positive role in osteoclastogenesis, but their relative importance in osteoclast differentiation is unclear. We report the discovery that activation of a singl...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wiley Subscription Services, Inc., A Wiley Company
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153134/ https://www.ncbi.nlm.nih.gov/pubmed/20200955 http://dx.doi.org/10.1002/jbmr.4 |