The Role of Lymphostatin/EHEC Factor for Adherence-1 in the Pathogenesis of Gram Negative Infection

Lymphostatin/EHEC factor for adherence-1 is a novel large toxin represented in various Gram negative bacteria, highly associated with the development of infectious diarrhea and hemolytic uremic syndrome. In vitro and in vivo experiments identified lymphostatin/EFA-1 as a toxin with a central role in...

Descripción completa

Detalles Bibliográficos
Autor principal: Klapproth, Jan-Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2010
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153230/
https://www.ncbi.nlm.nih.gov/pubmed/22069619
http://dx.doi.org/10.3390/toxins2050954
_version_ 1782209868805963776
author Klapproth, Jan-Michael A.
author_facet Klapproth, Jan-Michael A.
author_sort Klapproth, Jan-Michael A.
collection PubMed
description Lymphostatin/EHEC factor for adherence-1 is a novel large toxin represented in various Gram negative bacteria, highly associated with the development of infectious diarrhea and hemolytic uremic syndrome. In vitro and in vivo experiments identified lymphostatin/EFA-1 as a toxin with a central role in the pathogenesis of Gram negative bacteria, responsible for bacterial adhesion, intestinal colonization, immunosuppression, and disruption of gut epithelial barrier function.
format Online
Article
Text
id pubmed-3153230
institution National Center for Biotechnology Information
language English
publishDate 2010
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-31532302011-11-08 The Role of Lymphostatin/EHEC Factor for Adherence-1 in the Pathogenesis of Gram Negative Infection Klapproth, Jan-Michael A. Toxins (Basel) Review Lymphostatin/EHEC factor for adherence-1 is a novel large toxin represented in various Gram negative bacteria, highly associated with the development of infectious diarrhea and hemolytic uremic syndrome. In vitro and in vivo experiments identified lymphostatin/EFA-1 as a toxin with a central role in the pathogenesis of Gram negative bacteria, responsible for bacterial adhesion, intestinal colonization, immunosuppression, and disruption of gut epithelial barrier function. MDPI 2010-05-05 /pmc/articles/PMC3153230/ /pubmed/22069619 http://dx.doi.org/10.3390/toxins2050954 Text en © 2010 by the authors; licensee MDPI, Basel, Switzerland http://creativecommons.org/licenses/by/3.0/ This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Review
Klapproth, Jan-Michael A.
The Role of Lymphostatin/EHEC Factor for Adherence-1 in the Pathogenesis of Gram Negative Infection
title The Role of Lymphostatin/EHEC Factor for Adherence-1 in the Pathogenesis of Gram Negative Infection
title_full The Role of Lymphostatin/EHEC Factor for Adherence-1 in the Pathogenesis of Gram Negative Infection
title_fullStr The Role of Lymphostatin/EHEC Factor for Adherence-1 in the Pathogenesis of Gram Negative Infection
title_full_unstemmed The Role of Lymphostatin/EHEC Factor for Adherence-1 in the Pathogenesis of Gram Negative Infection
title_short The Role of Lymphostatin/EHEC Factor for Adherence-1 in the Pathogenesis of Gram Negative Infection
title_sort role of lymphostatin/ehec factor for adherence-1 in the pathogenesis of gram negative infection
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153230/
https://www.ncbi.nlm.nih.gov/pubmed/22069619
http://dx.doi.org/10.3390/toxins2050954
work_keys_str_mv AT klapprothjanmichaela theroleoflymphostatinehecfactorforadherence1inthepathogenesisofgramnegativeinfection
AT klapprothjanmichaela roleoflymphostatinehecfactorforadherence1inthepathogenesisofgramnegativeinfection

Ejemplares similares