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Consequences and Utility of the Zinc-Dependent Metalloprotease Activity of Anthrax Lethal Toxin

Anthrax is caused by the gram-positive bacterium Bacillus anthracis. The pathogenesis of this disease is dependent on the presence of two binary toxins, edema toxin (EdTx) and lethal toxin (LeTx). LeTx, the major virulence factor contributing to anthrax, contains the effector moiety lethal factor (L...

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Detalles Bibliográficos
Autores principales:	Bromberg-White, Jennifer, Lee, Chih-Shia, Duesbery, Nicholas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2010
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153234/ https://www.ncbi.nlm.nih.gov/pubmed/22069624 http://dx.doi.org/10.3390/toxins2051038

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