NetB, a Pore-Forming Toxin from Necrotic Enteritis Strains of Clostridium perfringens

The Clostridium perfringens necrotic enteritis B-like toxin (NetB) is a recently discovered member of the β-barrel pore-forming toxin family and is produced by a subset of avian C. perfringens type A strains. NetB is cytotoxic for avian cells and is associated with avian necrotic enteritis. This rev...

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Autores principales: Keyburn, Anthony L., Bannam, Trudi L., Moore, Robert J., Rood, Julian I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2010
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153261/
https://www.ncbi.nlm.nih.gov/pubmed/22069665
http://dx.doi.org/10.3390/toxins2071913
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author Keyburn, Anthony L.
Bannam, Trudi L.
Moore, Robert J.
Rood, Julian I.
author_facet Keyburn, Anthony L.
Bannam, Trudi L.
Moore, Robert J.
Rood, Julian I.
author_sort Keyburn, Anthony L.
collection PubMed
description The Clostridium perfringens necrotic enteritis B-like toxin (NetB) is a recently discovered member of the β-barrel pore-forming toxin family and is produced by a subset of avian C. perfringens type A strains. NetB is cytotoxic for avian cells and is associated with avian necrotic enteritis. This review examines the current state of knowledge of NetB: its role in pathogenesis, its distribution and expression in C. perfringens and its vaccine potential.
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spelling pubmed-31532612011-11-08 NetB, a Pore-Forming Toxin from Necrotic Enteritis Strains of Clostridium perfringens Keyburn, Anthony L. Bannam, Trudi L. Moore, Robert J. Rood, Julian I. Toxins (Basel) Review The Clostridium perfringens necrotic enteritis B-like toxin (NetB) is a recently discovered member of the β-barrel pore-forming toxin family and is produced by a subset of avian C. perfringens type A strains. NetB is cytotoxic for avian cells and is associated with avian necrotic enteritis. This review examines the current state of knowledge of NetB: its role in pathogenesis, its distribution and expression in C. perfringens and its vaccine potential. MDPI 2010-07-23 /pmc/articles/PMC3153261/ /pubmed/22069665 http://dx.doi.org/10.3390/toxins2071913 Text en © 2010 by the authors; licensee MDPI, Basel, Switzerland http://creativecommons.org/licenses/by/3.0/ This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Review
Keyburn, Anthony L.
Bannam, Trudi L.
Moore, Robert J.
Rood, Julian I.
NetB, a Pore-Forming Toxin from Necrotic Enteritis Strains of Clostridium perfringens
title NetB, a Pore-Forming Toxin from Necrotic Enteritis Strains of Clostridium perfringens
title_full NetB, a Pore-Forming Toxin from Necrotic Enteritis Strains of Clostridium perfringens
title_fullStr NetB, a Pore-Forming Toxin from Necrotic Enteritis Strains of Clostridium perfringens
title_full_unstemmed NetB, a Pore-Forming Toxin from Necrotic Enteritis Strains of Clostridium perfringens
title_short NetB, a Pore-Forming Toxin from Necrotic Enteritis Strains of Clostridium perfringens
title_sort netb, a pore-forming toxin from necrotic enteritis strains of clostridium perfringens
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153261/
https://www.ncbi.nlm.nih.gov/pubmed/22069665
http://dx.doi.org/10.3390/toxins2071913
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