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Bacterial Heat-Stable Enterotoxins: Translation of Pathogenic Peptides into Novel Targeted Diagnostics and Therapeutics

Heat-stable toxins (STs) produced by enterotoxigenic bacteria cause endemic and traveler’s diarrhea by binding to and activating the intestinal receptor guanylyl cyclase C (GC-C). Advances in understanding the biology of GC-C have extended ST from a diarrheagenic peptide to a novel therapeutic agent...

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Detalles Bibliográficos
Autores principales: Lin, Jieru E., Valentino, Michael, Marszalowicz, Glen, Magee, Michael S., Li, Peng, Snook, Adam E., Stoecker, Brian A., Chang, Chang, Waldman, Scott A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153287/
https://www.ncbi.nlm.nih.gov/pubmed/22069671
http://dx.doi.org/10.3390/toxins2082028