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Wnt10b Deficiency Results in Age-Dependent Loss of Bone Mass and Progressive Reduction of Mesenchymal Progenitor Cells

Wnt10b is a canonical Wnt ligand expressed in developing bone and has been linked to mesenchymal progenitor functions in mice and humans. Because Wnt signaling has been shown to play an important role in progenitor maintenance in a variety of adult tissues, we examined bone deposition and growth rat...

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Detalles Bibliográficos
Autores principales:	Stevens, Jennifer R, Miranda-Carboni, Gustavo A, Singer, Meredith A, Brugger, Sean M, Lyons, Karen M, Lane, Timothy F
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wiley Subscription Services, Inc., A Wiley Company 2010
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153316/ https://www.ncbi.nlm.nih.gov/pubmed/20499361 http://dx.doi.org/10.1002/jbmr.118

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