Acute Phosphate Restriction Leads to Impaired Fracture Healing and Resistance to BMP-2

Hypophosphatemia leads to rickets and osteomalacia, the latter of which results in decreased biomechanical integrity of bones, accompanied by poor fracture healing. Impaired phosphate-dependent apoptosis of hypertrophic chondrocytes is the molecular basis for rickets. However, the underlying pathoph...

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Detalles Bibliográficos
Autores principales: Wigner, Nathan A, Luderer, Hilary F, Cox, Megan K, Sooy, Karen, Gerstenfeld, Louis C, Demay, Marie B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2010
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153327/
https://www.ncbi.nlm.nih.gov/pubmed/19839770
http://dx.doi.org/10.1359/jbmr.091021

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