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Microdamage Repair and Remodeling Requires Mechanical Loading
Bone remodeling is necessary to avoid microdamage accumulation, which could lead to whole-bone failure. Previous studies have shown that this bone-repair mechanism is triggered by osteocyte apoptosis. Through the use of a rodent hindlimb suspension model and tibial four-point bending model, the effe...
Autores principales: | Waldorff, Erik I, Christenson, Katya B, Cooney, Laura A, Goldstein, Steven A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wiley Subscription Services, Inc., A Wiley Company
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153328/ https://www.ncbi.nlm.nih.gov/pubmed/19821772 http://dx.doi.org/10.1359/jbmr.091016 |
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